2002年

Saunders PTK., Maguire SM., Macpherson S., Fenelon MC., Sakakibara S., Okano H.: The RNA binding protein Musashi1 (Msi1) is expressed in the cytoplasm and nucleus of Sertoli cells in the rat testis from fetal life to adulthood.
Biology of Reproduction 66, 500-507, 2002.

Hirota Y., Sawamoto K., Okano H.: tincar encodes a novel transmembrane protein expressed in the Tinman-expressing cardioblasts of Drosophila.
Mech. Dev. 119S:271-275, 2002.

Uchida M., Hanai S., Uematsu N., Sawamoto K., Okano H., Miwa M., Uchida K.: Overexpression of poly(ADP-ribose) polymerase disrupts organization of cytoskeletal F-actin and tissue polarity in Drosophila.
J. Biol. Chem. 277, 6696-6702, 2002.

Matsuno K., Ito M., Hori K., Miyashita F., Suzuki S., Kishi N., Artravanis-Tsakonas S., Okano H.: Involvement of a proline-rich motif and a RING-H2 finger in a function of Deltex as a regulator of Notch signaling.
Development 129, 1049-1059, 2002.

Takasawa K.-I., Kitagawa K., Yagita Y., Sasaki T., Tanaka S., Ohtsuki T., Miyata T., Okano H., Hori M., Matsumoto M.: Increased proliferation of neural progenitor cells but reduced survival newborn cells in the contralateral hippocampus after focal cerebral ischemia in rats.
J. Cerebral Blood Flow and Metabolism 22, 299-307, 2002.

Iwai Y., Hirota Y., Ozaki K., Okano H., Takeichi M., Uemura T.: DN-cadherin-dependent synaptogenesis in the Drosophila visual system.
Mol. Cell. Neurosci. 19, 375-388, 2002.

Shibata M., Yamawaki T., Sasaki T., Hattori H., Hamada J., Fukuuchi Y., Okano H., Miura M.: Upregulation of Akt phosphorylation at the early stage of middle cerebral artery occlusion in mice.
Brain Res. 942, 1-10, 2002.

Shu H-J., Saito T., Watanabe H., Ito J-I., Takeda H., Okano H., Kawata S.: Expression of the Musashi1 gene encoding the RNA-binding protein in human hepatoma cell lines.
Biochem. Biophys. Res. Com. 293, 150-154, 2002.

Cuadrado A., Garcia-Fernandez L.F., Imai T., Okano H., Munoz A.: Neural RNA-binding protein Musashi-1 modulates tau pre-mRNA alternative splicing and is regulated by thyroid hormone in the developing rat brain.
Mol. Cell. Neurosci. 20, 198-210, 2002.

Shamloula H.K., Mbogho M.P., Pimentel A.C., Chrzanowska-Lightowlers Z.M.A., Hyatt V., Okano H., Venkatech T.R.: rugose (rg), a Drosophila A kinase Anchor Protein (DAKAP), is required for required for retinal pattern formation and interacts genetically with multiple signaling pathways.
Genetics 161, 693-710, 2002.

Yagita Y., Kitagawa K., Sasaki T., Miyata T., Okano H., Hori T., Matsumoto M.: Musashi1 and Nestin as useful markers of neuronal progenitor cells in rat hippocampus after forebrain ischemia.
J. Neurosci. Res. 69, 750-756, 2002.

Ogawa Y., Sawamoto K., Miyata T., Miyao S., Watanabe M., Toyama Y., Nakamura M., Bregman B.S., Koike M., Uchiyama Y., Okano H. : Transplantation of in vitro expanded fetal neural progenitor cells results in neurogenesis and functional recovery after spinal cord contusion injury in adult rats.
J. Neurosci. Res. 69, 925-933, 2002.

Murayama A., Matsuzaki Y., Kawaguti A., Shimazaki T., Okano H.: Flow cytometric analysis of stem cells in the developing and adult mouse brain.
J. Neurosci. Res. 69, 837-847, 2002.

Johansson CB., Lothian C., Molin M., Okano H., Lendahl U.: Nestin enhancer requirements for expression in normal and injured adult CNS.
J. Neurosci. Res. 69, 784-794, 2002.

Kanemura Y., Mori H., Kobayashi S., Islam O., Kodama E., Yamamoto A., Nakanishi Y., Arita N., Yamasaki M., Okano H., Miyake J., Hara M.: Evaluation of in-vitro proliferative activity of human fetal neural stem cell.
J. Neurosci. Res. 69, 869-879, 2002.

Kuranaga E., Kanuka H., Igaki T., Sawamoto K., Ichijo H., Okano H., Miura M.: Reaper-mediated inhibition of DIAP1-induced DTRAF1 degradation results in activation of JNK in Drosophila.
Nature Cell Biol. 4. 705-710, 2002.

Okano H., Yoshizaki T., Shimazaki T., Sawamoto K.: Isolation and transplantation of Dopaminergic Neurons and Neural Stem Cells.
Parkinson & Related Disorders. 9, 23-28, 2002.

Okano H., Imai T., Okabe M.: Musashi: a translational regulator of cell fates.
J. Cell Sci. 115, 1355-1359, 2002.

Okano H.: The stem cell biology of the central nervous system.
J. Neurosci. Res. 69, 698-707, 2002.

Okano H.: Neural stem cells: progression of basic research and perspective for clinical application.
Keio J. Med. 51. 115-128, 2002.

Kanemura Y., Sakakibara S., Okano H.: Identification of Musashi1-positive cells in human normal and neoplastic neuroepithelial tissue by immunohistochemical methods.
In _Methods in Molecular Biology, Vol. 198: Neural Stem Cells: Methods and Protocol_ (ed. Zigova T, Sanberg PR and Sanchez-Ramos JR). Humana Press Inc., Totowa, NJ, pp. 273-281, 2002.

Sakakibara S., Nakamura Y., Koike M., Takano H., Uchiyama Y., Noda T., Okano H.: RNA-binding protein Musashi family, roles for CNS stem cells and a subpopulation of ependymal cells revealed by targeted disruption and antisense ablation.
Proc. Natl. Acad. Sci. USA 99, 15194-15199, 2002.

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