2020年

“YAP-dependent necrosis occurs in early stages of Alzheimer’s disease and regulates mouse model pathology.”
Tanaka H, Homma H, Fujita K, Kondo K, Yamada S, Jin X, Waragai M, Ohtomo G, Iwata A, Tagawa K, Atsuta N, Katsuno M, Tomita N, Furukawa K, Saito Y, Saito T, Ichise A, Shibata S, Arai H, Saido T, Sudol M, Muramatsu SI, Okano H, Mufson EJ, Sobue G, Murayama S, Okazawa H.
Nat Commun. 2020 Jan 24;11(1):507. doi: 10.1038/s41467-020-14353-6. [PubMed]

 

“In vivo monitoring of remnant undifferentiated neural cells following human iPS cell-derived neural stem/progenitor cells transplantation.”
Tanimoto Y, Yamasaki T, Nagoshi N, Nishiyama Y, Nori S, Nishimura S, Iida T, Ozaki M, Tsuji O, Ji B, Aoki I, Jinzaki M, Matsumoto M, Fujibayashi Y, Zhang MR, Nakamura M, Okano H. Stem Cells Transl Med. 2020 Jan 6. doi: 10.1002/sctm.19-0150. [PubMed] プレスリリース 

“Ropinirole, a New ALS Drug Candidate Developed Using iPSCs.”
Okano H, Yasuda D, Fujimori K, Morimoto S, Takahashi S.
Trends Pharmacol Sci. 2020 Jan 8. pii: S0165-6147(19)30274-3. doi: 10.1016/j.tips.2019.12.002. [PubMed]